Frontline Plus (COMBO) for Large Dogs 45-88 lbs (Purple)

101 customer reviews
Frontline Plus (COMBO) for Large Dogs 45-88 lbs (Purple)

Price: $29.35$41.09

  • $41.09 $29.35
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Frontline Combo Flea and Tick Control for Dogs

One of the most popular flea and tick control treatments for dogs, Frontline Combo is as an easy-to-apply topical treatment. Frontline Combo kills fleas, ticks, and all flea life stages. Due to its waterproof property, Frontline Combo remains effective even after your dog gets wet and gives lasting protection for an entire month. This highly effective monthly treatment is suitable for all dog breeds.

It kills 100% fleas within 24 hours and ticks and chewing lice within 48 hours of application. Fipronil and S-Methoprene are the active ingredients present in Frontline Combo. The insecticide Fipronil attacks the central nervous system of parasites, paralyze them and eventually kill them. The other ingredient (s)-Methoprene is an IGR - Insect Growth Regulator that inhibits the growth of juvenile stages of parasites and prevents further re-infestations.

Frontline Combo provides month-long protection to dogs and protects them from flea and tick-borne diseases. The topical treatment kills all flea life stages including egg, larvae, and pupae and thus, eliminates chances of re-infestations.

Please be informed that as Merial is now part of Boehringer Ingelheim, the manufacturer’s name may vary on the product packs according to the stock availability.

Frontline Spray

Frontline Spray is an effective and unique solution designed for both cats and dogs. It efficiently treats flea and tick infestations in dogs, cats, puppies, and kittens. This treatment eliminates 100% fleas within 24 hours of administration. The frontline spray also effectively controls brown dog ticks when applied on a monthly basis and paralysis ticks in every 3 weeks of application. It is a highly recommended remedy which regulates Flea Allergy Dermatitis (FAD) as well. More Info on Frontline Spray.


Manufacturer Merial / Boehringer Ingelheim
  • Topical treatment for flea and tick infestations
  • Kills fleas, lone star ticks, American ticks, brown dog ticks and deer ticks
  • Suitable for all breeds of 8 weeks and older puppies and dogs
  • Waterproof treatment that remains effective even after swimming and bathing
  • Protects against flea and tick borne diseases
  • Aids in treatment of Flea Allergy Dermatitis (FAD)
  • As per the weight and size of dogs, Frontline Combo is made available in four different color-coded packs. Please refer dosage table for details.
  • Weigh your pet and choose the appropriate pack. Part the fur behind the neck of the pet. Make sure it is between the shoulder blades so that the pet cannot lick it.
  • Place the tip of the pipette on the spot and squeeze out all the content. Allow the application site to be dry. For small dogs and medium sized dogs, apply at just one spot while for larger dogs apply at 4-5 spots moving across the backbone to the base of the tail.
  • It is suitable for breeding, pregnant and nursing female dogs while it is advised to take veterinarian guidance before treating sick, aged and debilitated dogs with Frontline Combo.
  • Dosage:

    Color Code


    Dog Size


    0.67 ml

    0-22 lbs


    1.34 ml

    23-44 lbs


    2.68 ml

    45-88 lbs


    4.02 ml

    89-132 lbs

  • Do not treat puppies under 8 weeks of age with Frontline Combo.
  • Do not use on cats or other animals.
  • Let the application site be completely dry. Do not allow the pet to lick the application site.
  • Do not allow children and other pets to groom or play with the treated pet until the applied sites is completely dry.
  • Keep away from pet’s eyes and mouth.
  • If the solution enters the pet’s eyes accidentally, then flush the eyes with a lot of water.
  • It contains inflammable substance and so needs to be kept away from excessive heat or fire.
  • Keep away from children, food items and animal feeds.
  • Do not drink or smoke while applying the treatment.
  • It proves toxic for human consumption. In case of accidentally swallowing contact Poison Control Center at the earliest.
  • Fipronil
  • (S)-methoprene
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MsgIcon Customer Reviews (101)
Frontline Plus (COMBO) for Dogs

Rated 4.9/5 based on 101 ratings

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Good Product

A Really Good Product In My Opinion.

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Literally Amazing

An Amazing Topical Flea And Tick Treatment.

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Branded And Brilliant

Branded Products Are Really Good. Plus, I Get Them At Reasonable Rates From You Guys.

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Amazing Efficacy

Proper Product. Has Amazing Efficacy.

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Was Suggested

I Was Suggested To Give This A Try. And Boy, It Worked Out Well.

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