Frontline Plus for Dogs

307 customer reviews

Frontline Plus for Small Dogs up to 22lbs (Orange)

You Pay
3 Doses
6 Doses
12 Doses

Frontline Plus for Medium Dogs 23-44 lbs (Blue)

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3 Doses
6 Doses
12 Doses

Frontline Plus for Large Dogs 45-88 lbs (Purple)

You Pay
3 Doses
6 Doses
12 Doses

Frontline Plus for Extra Large Dogs over 89 lbs (Red)

You Pay
3 Doses
6 Doses
12 Doses

Frontline Plus Spray

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100 Ml
250 Ml

Frontline Plus Flea and Tick Control for Dogs

One of the most popular flea and tick control treatments for dogs, Frontline Plus is as an easy-to-apply topical treatment. Frontline Plus kills fleas, ticks, and all flea life stages. Due to its waterproof property, Frontline Plus remains effective even after your dog gets wet and gives lasting protection for an entire month. This highly effective monthly treatment is suitable for all dog breeds.

It kills 100% fleas within 24 hours and ticks and chewing lice within 48 hours of application. Fipronil and S-Methoprene are the active ingredients present in Frontline Plus. The insecticide Fipronil attacks the central nervous system of parasites, paralyze them and eventually kill them. The other ingredient (s)-Methoprene is an IGR - Insect Growth Regulator that inhibits the growth of juvenile stages of parasites and prevents further re-infestations.

Frontline Plus provides month-long protection to dogs and protects them from flea and tick-borne diseases. The topical treatment kills all flea life stages including egg, larvae, and pupae and thus, eliminates chances of re-infestations.

Please be informed that as Merial is now part of Boehringer Ingelheim, the manufacturer’s name may vary on the product packs according to the stock availability.

Frontline Spray

Frontline Spray is an effective and unique solution designed for both cats and dogs. It efficiently treats flea and tick infestations in dogs, cats, puppies, and kittens. This treatment eliminates 100% fleas within 24 hours of administration. The frontline spray also effectively controls brown dog ticks when applied on a monthly basis and paralysis ticks in every 3 weeks of application. It is a highly recommended remedy which regulates Flea Allergy Dermatitis (FAD) as well. More Info on Frontline Spray.

Manufacturer Merial / Boehringer Ingelheim
  • Topical treatment for flea and tick infestations
  • Kills fleas, lone star ticks, American ticks, brown dog ticks and deer ticks
  • Suitable for all breeds of 8 weeks and older puppies and dogs
  • Waterproof treatment that remains effective even after swimming and bathing
  • Protects against flea and tick borne diseases
  • Aids in treatment of Flea Allergy Dermatitis (FAD)
  • As per the weight and size of dogs, Frontline Plus is made available in four different color-coded packs. Please refer the dosage table for details.
  • Weigh your pet and choose the appropriate pack. Part the fur behind the neck of the pet. Make sure it is between the shoulder blades so that the animal cannot lick it.
  • Place the tip of the pipette on the spot and squeeze out all the content. Allow the application site to be dry. For small dogs and medium-sized dogs, apply at just one spot while for larger dogs apply at 4-5 spots moving across the backbone to the base of the tail.
  • It is recommended for breeding, pregnant and nursing female dogs while it is advised to take veterinarian guidance before treating sick, aged and debilitated dogs with Frontline Plus.
    • Dosage:

      Color Code


      Dog Size


      0.67 ml

      0-22 lbs


      1.34 ml

      23-44 lbs


      2.68 ml

      45-88 lbs


      4.02 ml

      89-132 lbs

  • Do not treat puppies under 8 weeks of age with Frontline Plus.
  • Do not use on cats or other animals.
  • Let the application site be completely dry. Do not allow your dog to lick the application site.
  • Do not allow children and other pets to groom or play with the treated animal until the applied site is completely dry.
  • Keep away from pet’s eyes and mouth.
  • If the solution enters the pet’s eyes accidentally then flush with a lot of water.
  • It contains inflammable substance and so needs to be kept away from excessive heat or fire.
  • Keep away from children, food items and animal feeds.
  • Do not drink or smoke while applying the treatment.
  • It proves toxic for human consumption. In case of accidental ingestion contact Poison Control Center at the earliest.
  • Fipronil
  • (S)-methoprene
Frequently Asked Questions

What is the most important thing I should know about Frontline Plus topical?

Frontline Plus topical is a fast-acting, long-lasting, and effective flea and tick treatment for dogs. It kills all stages of the brown dog tick, American dog tick, lone star tick, and deer tick (the major carrier of Lyme disease). It also eliminates flea eggs, flea larvae, chewing lice and controls sarcoptic mange.

How long does it take Frontline Plus to work?

Frontline Plus’ active ingredients should kill 100% of adult fleas within 12 hours and all ticks within 48 hours in ideal conditions.

Is Frontline Plus safe for dogs?

Frontline Plus spot-on has been shown to be safe for puppies as young as 8 weeks old. It is approved for use on all dogs, including breeding, pregnant, and lactating bitches.

How to use Frontline Plus for dogs?

Frontline Plus can be applied on dogs in three easy steps:

  • Remove applicator from the box.
  • Open applicator. Hold the applicator upright and break the snap-off to open.
  • Apply Frontline Plus. Place the applicator tip just above the skin and squeeze on to the skin between the shoulder blades.

Can you use Frontline Plus and Seresto together?

Yes, you can use Frontline Plus and Seresto Collar together.

Can Frontline Plus topical for dogs be used on cats?

No, using Frontline Plus topical treatment for dogs is specifically formulated for dogs, and it can be lethal if used on cats or any other animals.

Can I use Capstar with Frontline Plus?

Yes, you can use Capstar with Frontline Plus.

What are the potential side effects of Frontline Plus?

Pets may feel temporary irritation at the application site of the product. Consult a veterinarian right away if symptoms persist or worsen within a few days following application.

What happens if I overdose my pet with Frontline Plus spot-on?

Contact your veterinarian immediately in such circumstances.

Do I need to use other flea & tick treatments while using Frontline Plus for Dogs?

Frontline Plus flea and tick treatment offers full protection from fleas, ticks and ear mites. So, you don’t need to use any other flea and tick treatments while your dog is on Frontline Plus.

My dog doesn’t go outside much; do I still need to treat them for fleas and ticks?

Fleas and ticks are a threat to dogs even if your dog stays indoors. Untreated pets may face serious illness due to fleas and ticks. Prevention treatments like Frontline Plus topical treatment helps prevent such pesky parasites, so it is essential to treat them.

Is the Frontline Plus that you get from the vet the same as what you get from the online store?

Yes, it is the same.

Do you Ship Frontline Plus to the United States?

Yes. We ship it to the United States. Moreover, our Frontline Plus’ price is comparatively much lower than most online stores.

Can my dog get wet right after applying Frontline Plus?

Frontline Plus spot-on is a water-proof formula but it is recommended to refrain your pet from coming in contact with water for the next 48 hours after applying Frontline Plus.

Should I reapply Frontline Plus if I see more fleas on my dog or cat soon after application?

Frontline Plus is a monthly treatment and it should never be applied at an interval smaller than 30 days.

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MsgIcon Customer Reviews (307)
Frontline Plus for Dogs

Rated 4.9/5 based on 307 ratings

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Diane Miller
Frontline plus for dogs

My dogs will not chew any of the chewable flea treatments. I’m going to try frontline plus as I have read that it’s very effective.

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Melissa Thomas
Pet care made easy

I order all my dog’s heart worm and flea/tick prevention from Canada Pet Care because the prices are fantastic and it’s so easy to order. Thank you Canada Pet Care!!

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Robert Palmer
R. Palmer

Service was good and delivery was made as promised! I am happy with this order.

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David Parker
Great customer service

Quick and efficient service. Prices are much lower than other places I've purchased the same item.

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The shipping was decent time and site easy to order

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Have A Question?
What differences between frontline plus comb and frontline plus
Frontline Combo shows the same benefits as the Frontline Plus whereas the difference lies in their names depending on the countries where they are sold.
| May 12, 2022
(17) | (4)
Does Frontline Plus cause skin irritation?
| Mar 29, 2022
(17) | (4)
Can a very small dose be used on grown cats? I have the small mm applicator.
cat should be 8 weeks old.
| Jan 02, 2022
(17) | (2)
Can I put a second application of Frontline flea treatment on my dog if I did not apply the first dose correctly?
Please ask your Vet
| Aug 02, 2021
(17) | (3)
what is the difference between Frontline plus and spot on?
Both products kill fleas and ticks on your pet, however, FRONTLINE Plus also stops flea eggs from hatching and infesting your home.
| Jul 01, 2021
(17) | (5)
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