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Frontline Plus for Dogs

486 reviews (4.8/5)
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Frontline Plus for Small Dogs up to 22lbs (Orange)

Pack
QTY
Price
You Pay
3 Doses
$46.87
$33.48
6 Doses
$79.21
$56.58

Frontline Plus for Medium Dogs 23-44 lbs (Blue)

Pack
QTY
Price
You Pay
3 Doses
$54.22
$38.73
6 Doses
$98.32
$70.23

Frontline Plus for Large Dogs 45-88 lbs (Purple)

Pack
QTY
Price
You Pay
3 Doses
$58.63
$41.88
6 Doses
$107.14
$76.53

Frontline Plus for Extra Large Dogs over 89 lbs (Red)

Pack
QTY
Price
You Pay
3 Doses
$63.04
$45.03
6 Doses
$111.55
$79.68

Frontline Plus Flea & Tick Treatment for Dogs

Frontline Plus for Dogs is the leading name in canine flea and tick protection. This fast-acting and long-lasting topical treatment offers comprehensive protection against fleas and ticks. It effectively kills all life stages of fleas, including eggs, larvae, and pupae, as well as all stages of ticks—larvae, nymphs, and adults. This means your dog is protected not only from visible parasites but also from the hidden, immature stages of these pests that may be present in your home.

Frontline Plus topical treatment for dogs has been trusted by dog parents for over 20 years. It effectively protects against parasites that can transmit harmful diseases, such as Lyme disease and Rocky Mountain Spotted Fever. Frontline Plus is generally considered safe for most dog breeds, including pregnant, breeding, and nursing dogs. With just one application each month, it provides year-round protection from a variety of parasites for your furry friends.

Recommended For:

  • Puppies & dogs.
  • Frontline Plus for Dogs is recommended for puppies and dogs from 8 weeks of age, weighing at least 5 lbs.

Frontline Plus for Dogs Coverage:

  • Kills adult fleas.
  • Kills flea eggs, larvae and pupae, preventing all flea life stages from developing.
  • Stops existing flea infestations and prevents new infestations.
  • Eliminates fleas, which may cause flea allergy dermatitis.
  • Controls ticks at various life stages (larva, nymph and adult).
  • Effective against brown dog ticks, American dog ticks, lone star ticks and black-legged (deer) ticks.
  • Kills ticks that may transmit tick-borne diseases, reducing the risk of exposure.
  • Eliminates chewing lice infestations.
  • Helps control sarcoptic mange infestations.

Why Should You Buy Frontline Plus for Your Dog?

  • Convenient, monthly topical treatment provides ease of dosing.
  • Trusted formula for flea & tick protection.
  • Long-lasting, fast-acting and waterproof formula.
  • Kills fleas and ticks at all life stages, providing comprehensive protection.
  • Eliminates ticks that may transmit tick-borne diseases. This helps reduce the risk of exposure.
  • Kills parasites after contact with the treated dog, saving your dogs from painful bites.
  • Stays effective after bathing, water immersion or exposure to sunlight, once the product has dried.
  • Suitable for puppies as young as 8 weeks of age.
  • Can be used in pregnant, breeding and lactating dogs, when administered as indicated.
  • Available in four different weight-specific packs to suit dogs of different sizes.

How Does Frontline Plus for Dogs Work?

Frontline Plus for dogs contains two active ingredients, fipronil and s-methoprene. After application, the formula quickly spreads and covers the entire body of the dog. The ingredients localize on your dog's skin surface, in the hair and in the sebaceous glands. These glands work as a reservoir and continuously replenish the formula on the dog's skin and coat.

Fipronil targets the adult fleas and ticks on your pet. S-methoprene prevents the laying of fertile eggs and stops larval and pupal development. Thus, it prevents the re-infestation of your pet and contamination of your home.

Directions
  • Weigh your dog to select the suitable dosage pack.
  • Take an applicator tube out of the pack.
  • Open the applicator, holding it upright with the foil side toward you.
  • Snap the applicator tip.
  • Part the dog's hair between the shoulder blades. Place the tip of the applicator above the dog's skin and squeeze.
  • Apply the entire contents of the tube in a single spot directly onto the dog's skin.
  • Avoid applying it on top of the hair coat.
  • Do not contact the treated area until dry.

Frontline Plus for Dogs Dosing Guide:

Dog Size Dog Weight (lbs) Pack Color Tube Volume (ml) Active Ingredients (g/L) Doses Administered
Small Dogs Up to 22.0 Orange 0.67 9.8% Fipronil
8.8% (S)-methoprene
One
Medium Dogs 22.1 – 44.0 Blue 1.34 9.8% Fipronil
8.8% (S)-methoprene
One
Large Dogs 44.1 – 88.0 Purple 2.68 9.8% Fipronil
8.8% (S)-methoprene
One
Extra Large Dogs Over 88 Red 4.02 9.8% Fipronil
8.8% (S)-methoprene
One
Safety

Frontline Plus for Dogs is for external use on puppies and dogs only. Do not administer it orally. It is not indicated for use in cats or humans. You should keep this topical product out of the reach of children, uninformed people and pets. Do not allow children or anyone to come in contact with the application site until the application is dry.

Frontline Plus can be used in pregnant, breeding and lactating dogs, when applied as indicated. Ensure to avoid the product's contact with the pet's eyes or mouth. It is not suitable for use in puppies younger than 8 weeks of age or weighing less than 5 lbs. Do not allow your dog to ingest the treatment.

Do not use or store the product near heat or open flame. Avoid contaminating water, food or feed during storage and disposal. Wash your hands thoroughly after handling the product.

Storage Guide:
Store unused Frontline Plus in the original container.

Ingredients
  • Fipronil
  • (S)-methoprene
Frequently Asked Questions

Why do I see fleas on my dog after applying Frontline Plus?

Frontline Plus kills fleas by interrupting their nervous system functions. This makes fleas hyperactive just before dying. These fleas rise, often surfacing on the pet's coat. Meaning, when you see active fleas on your pet's coat after treating them with Frontline Plus, it indicates that the treatment is working.

Does Frontline Plus stop fleas from jumping on my dog?

Frontline Plus kills fleas once the parasites come in contact with the treated pet. Fleas and ticks do not need to bite your dog to be killed.

Can I use Frontline Plus on any breed of dog?

Frontline Plus is usually safe for all dog breeds. Please talk to your vet before any treatment for your dog.

Is it safe to use Frontline Plus for dogs on cats?

You should always use products on pet species for which they have been specifically developed and licensed for. Frontline Plus for dogs must only be used on dogs and should not be applied to any other animal species.

Can I use Frontline Plus for dogs with other treatments?

You should consult a veterinarian before using Frontline Plus with other treatments.

Can I take my dog for swimming right after applying Frontline Plus?

Your dog should remain dry for 24 hours after applying Frontline Plus.

How often should I apply Frontline Plus to my dog?

Frontline Plus should be applied once every month for protection against fleas, ticks, chewing lice and sarcoptic mange infestations.

What happens if my dog licks Frontline Plus after application?

If your dog licks Frontline Plus shortly after application, the pet may salivate excessively for a short time. If it continues or you see anything unusual, talk to a vet.

I still see fleas on my pet after applying Frontline Plus; should I apply one more dose?

No. Frontline Plus keeps working for one month after application. The fleas you see may have emerged recently from the environment, which shall be killed by the treatment.

Should I treat all my dogs and cats with Frontline Plus?

Yes. All pets in the household should be treated with species-appropriate flea control products.

MsgIcon Customer Reviews (486)
Frontline Plus

Rated 4.8/5 based on 486 ratings

NG
Nadia Glynn
Trusted over the years

Been using Frontline Plus on and off for years now and it still works fine for basic flea prevention.

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Sterling
Old reliable option

Been using Frontline Plus on and off for years and it still works fine for regular flea control without much hassle.

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Phoenix
Trusted routine product

Been using Frontline Plus for a long time and it still works fine for regular use.

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Mikayla T. Salazar
Been using for years

Frontline Plus has been part of our routine for a long time and still works fine.

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Mikayla T. Salazar
Been using for years

Frontline Plus has been part of our routine for a long time and still works fine.

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