Heartgard Plus for Dogs

723 customer reviews

Heartgard Plus Chewables Small Dogs up to 25lbs (Blue)

You Pay
6 Doses
12 Doses

Heartgard Plus Generic Nuheart Small Dogs upto 25lbs (Blue)

You Pay
6 Tablets
12 Tablets

Heartgard Plus Chewables for Medium Dogs 26-50lbs (Green)

You Pay
6 Doses
12 Doses

Heartgard Plus Generic Nuheart Medium Dogs 26-50lbs (Green)

You Pay
6 Tablets
12 Tablets

Heartgard Plus Chewables for Large Dog 51-100lbs (Brown)

You Pay
6 Doses
12 Doses

Heartgard Plus Generic Nuheart for Large Dogs 51-100lbs (Red)

You Pay
6 Tablets
12 Tablets

Heartgard Plus Chewables - Heartworm Treatment For Dogs

Heartgard Plus is a beef-flavored chewable to prevent heartworm infection in dogs. It also treats and controls preexisting hookworm and roundworm infections. Heartworms, spread by mosquitoes, can result into fatal diseases when prevented with heartworm preventives. Hence, to protect your pet from deadly diseases, Heartgard is a full proof solution. Heartgard Plus tablets treat small, medium and large sized dogs that falling under three weight ranges – 0-25 lbs, 26-50 lbs and 51-100 lbs respectively. Available in 6-dose and 12-dose packets, these palatable tablets are given as a monthly dosage.

Heartgard Plus contains two potent ingredients - Ivermectin and Pyrantel. The active ingredient Ivermectin eliminates the immature form of heartworms and the other ingredient pyrantel removes hookworms and roundworms. The oral treatment when given monthly protects your dog against dangerous heartworm disease.

It effectively prevents heartworm disease and can be administered monthly starting from 6 weeks old puppies.

Nuheart for Dogs

Nuheart - a generic heartgard is an effective heartworm treatment for dogs. Nuheart is a generic version of Heartgard with exactly the same ingredient as in Heartgard. Nuheart is a meat flavored monthly tablet that is easy to dose. It is safe to use for dogs and puppies over 6 weeks of age.

Read More: Difference Between Heartgard Plus VS Generic Nuheart

Manufacturer Merial / Boehringer Ingelheim
  • The palatable tablets are loved by dogs making the treatment quite easy to administer
  • Prevents heartworm disesase
  • Treats and controls roundworms and hookworms
  • Before starting this preventive program, get your dog tested for heartworm infection.
  • For dogs tested with no heartworm infection, monthly administering of Heartgard Plus is a must. Give the tablets every month on the same date to prevent heartworm infection.
  • By chance if you miss giving a dose and 30 days have passed by since the last dosage, immediately administer Heartgard Plus and resume the monthly treatment schedule.
  • Continuous treatment for 12 months is a must. Administered orally, the palatable tablet can be broken into pieces for ease of swallowing. For dogs this tasteful tablet is a treat.
  • Remove tablets only when needed and protect the packet from sunlight. While administering, avoid contact with eyes. 

Heartgard Plus Dosage for Dogs/Puppies (6 weeks and older puppies):

Pack Size Strength Dosage
Heartgard Plus Blue
(up to 25lbs)
68mcg Ivermectin, 57mg Pyrantel One Dose Per Month
Heartgard Plus Green
136mcg Ivermectin, 114mg Pyrantel One Dose Per Month
Heartgard Plus Brown
272mcg Ivermectin, 227mg Pyrantel One Dose Per Month
  • Test the puppies and dogs for heartworm infection prior to starting the treatment.
  • It is advisable that the pet should chew the tablet rather than swallow it.
  • The monthly dose of the tablet should be continued throughout the year.
  • Skipping treatment in winter months is strictly not advisable as the pets might catch up on infections during this time.
  • In case the dosage is missed for more than two months, you need to consult a veterinarian and take his/her advice for further treatment. 

Caution:Collies including Border Collies and other breeds are sensitive to Ivermectin. Please consult your vet before giving this treatment or look for alternatives to Ivermectin for the treatment of parasites.


Heartgard Plus Ingredients:

Ivermectin, Pyrantel

Nuheart Ingredient:


Frequently Asked Questions

What is Heartgard Plus Chewable?

Heartgard Plus chewables are highly-palatable, beef-flavored chews for the prevention of heartworms in dogs and the treatment and control of roundworms and hookworms. Heartgard Plus remains effective for one full month.

How do dogs get heartworms?

Heartworms are transmitted through mosquito bites. When an infected mosquito bites a dog, heartworm larvae get deposited on the skin. These larvae enter the skin through the bite wound and make their way toward the heart.

How does Heartgard Plus for dogs work?

Heartgard Plus chews contains ivermectin and pyrantel pamoate as its active ingredients. Ivermectin is an antiparasitic that prevents heartworms, whereas, pyrantel is antihelmintic that treats and control roundworms and hookworms.

How should I dose Heartgard Plus Chewables and how often?

Heartgard Plus soft chew is a monthly heartworm prevention treatment, so it should be administered regularly every month for continuous protection. It can be given directly to your dog or it may be added to the food after breaking the chew into small pieces.

What should I keep in mind while using Heartgard Plus for dogs?

Heartgard Plus chewable tablets contains Ivermectin and, according to the studies, certain dogs of the Collie breed are more sensitive to its effects when administered at elevated dose levels than other dog breeds. Therefore, it should be used with caution in collies and other herding dog breeds. Moreover, a heartworm test must be performed before starting this prevention treatment and 6 months after using this treatment as already present microfilaria take 6 months to mature.

Are there any health effects if I switch to Heartgard from any other heartworm preventatives?

Ideally, this should not cause any issues. Heartgard Plus is a trusted heartwormer and is safe for dogs. However, it is always safe to consult your veterinarian if your pet has ever had an allergic reaction to any of the ingredients in the product, including beef.

What happens if I miss giving a dose of Heartgard Plus heartworm treatment?

If you miss giving a dose, give it as soon as you remember. Do not double the dose.

What happens if I overdose my dog on Heartgard Plus Chewables by mistake?

Seek veterinary assistance immediately.

What is the weight or age requirement to give my dog Heartgard Plus?

Heartgard Plus chews is suitable for use for dogs 6 weeks of age and older. There is no minimum age requirement.

In what sizes and options are Heartgard Plus Chewables for dogs available?

Heartgard Plus is available in 3 dosage strengths:

  • Heartgard Plus Blue for Small Dogs up to 25lbs
  • Heartgard Plus Green for Medium Dogs 26-50lbs
  • Heartgard Plus Brown for Large Dogs 51-100lbs
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Heartgard Plus for Dogs

Rated 4.8/5 based on 723 ratings

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Did Well

It is one of its kind, your dog is always protect from the fleas

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flea eradication

The multi formula seems to have worked well than what we bought from a local store here.

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Nylda Santiago
My Health dog

Excellent price, time

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Linda Presley


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Rose Mays
Heartguard Plus

As advertised good price , quick shipping!

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Have A Question?
Can you use heart guard plus for heart worms and brave to for ticks and fleas ?
Yes, Bravecto protects dogs from fleas and ticks, whereas Heartgard Plus prevents heartworm disease. You may use them concurrently. Consult with your vet before administration of these treatments.
| Aug 16, 2022
(17) | (4)
What flea medicine do you suggest for dogs? They range in weight from 60-65 pounds to 100 lbs. Also What do you suggest for flea meds for cats? min. wt. is 10 lbs.
We carry a range of flea & tick treatments both for dogs and cats. We recommend you to consult a vet for a suitable flea and tick treatment for your pets. Please visit our website https://www.canadapetcare.com/ to select the product depending upon your vet's recommendations.
| Aug 05, 2022
(17) | (4)
Do I need a prescription to order Heartguard Plus?
| Aug 03, 2022
(17) | (4)
Why did mine come in red box instead of green?
It comes in four different pack sizes and color codes for different dog weight sizes.
| Jul 08, 2022
(17) | (4)
Can I order with out rx
| Mar 25, 2022
(17) | (4)
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