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Revolution Plus is veterinarians' #1 choice for cats according to Zoetis Pet Care. With over 25 years of proven protection of Revolution (selamectin), Revolution Plus offers broad-spectrum protection you can trust for your kittens and cats. This topical treatment for cats comes with a unique dual action formula (selamectin and sarolaner), meaning it is twice as tough on the parasites that cause harm and discomfort to your feline.
Revolution Plus once-monthly topical solution for cats comes in a quick-drying, small-volume and non-greasy single-use applicator for easy and mess-free application. It gives you the confidence of protecting your cats against the parasites that any cat or kitten regularly comes in contact with. Each dose effectively safeguards felines from fleas, flea tapeworms, ear mites, roundworms, hookworms and heartworm disease for one month. In addition, this all-in-one treatment for cats kills 4 types of ticks for a complete month with just one dose. Give your cats the much-needed inside-out protection in the form of convenient monthly spot-on Revolution Plus.
Selamectin, Sarolaner
Revolution Plus combines two powerful active ingredients, selamectin and sarolaner. This combination provides a broader protection against both external and internal parasites with this dual-action formula.
Selamectin interferes with the glutamate-gated chloride channels, causing paralysis and death of the parasites, including roundworms, hookworms and heartworms. Sarolaner causes increased nerve stimulation in the parasites, such as fleas, ticks and ear mites and kills them. The unique bi-modal action of selamectin and sarolaner protects against fleas and ear mites for a complete month.
Revolution Plus began killing fleas within 12 hours of treatment and killed more than 98% of fleas within 24 hours, as per a laboratory study, stated in the product label. The label also indicates the onset of tick-killing activity within 24 hours of administration. The combination of selamectin and sarolaner is 100% effective in preventing the development of heartworms in cats infected with heartworm larvae (Dirofilaria immitis) 30 days before treatment, according to lab studies referenced in the label.
| Cat Size | Cat Weight (lbs) | Pack Color | Tube Volume (ml) | Selamectin Strength (mg/tube) | Sarolaner Strength (mg/tube) | Doses Administered |
| Kittens & Small Cats | 2.8 – 5.5 | Yellow | 0.25 | 15 | 2.5 | One |
| Medium Cats | 5.6 – 11.0 | Orange | 0.50 | 30 | 5.0 | One |
| Large Cats | 11.1 – 22.0 | Green | 1.00 | 60 | 10.0 | One |
| For Cats over 22.0 lbs, administer the appropriate combination of Revolution Plus tubes. | ||||||
Revolution Plus is not indicated for use in humans. You should keep these topical products out of the reach of children, uninformed people and pets. Do not allow children or anyone to come in contact with the application site until four hours after the application. Individuals with known hypersensitivity to any of the active ingredients should consult their healthcare professional before applying it to a cat.
This is a flammable treatment. Keep it away from heat, sparks, open flames or other sources of ignition. This topical treatment should be used with caution in cats with a history of seizures or neurologic disorders. Avoid applying it to broken skin. Do not apply it when the cat’s coat is wet.
The safe use of Revolution Plus has not been evaluated in kittens less than 8 weeks of age and pregnant, breeding or lactating cats. Field studies suggest that Revolution Plus can be used with other treatments, including vaccines, cestocidal anthelmintics, antibacterials, sedatives, anesthetics, opioid analgesics, corticosteroids, and NSAIDs.
Revolution Plus is approved for use in kittens and cats 8 weeks of age and older, weighing at least 2.8 lbs. Do not apply it to kittens younger than 8 weeks.
There is no indication of bathing after treatment with Revolution Plus. It is, however, advisable to bathe and towel-dry the feline animal before applying the treatment. Talk to your vet for expert recommendations.
Revolution Plus prevents the development of adult heartworms when administered to cats within 1 month of exposure to infective (L3) Dirofilaria immitis larvae. It eliminates the tissue stage of heartworm larvae for one month after infection.
Cats with a negative heartworm test before the initiation of Revolution Plus should be tested 3-4 months after initiating the treatment. Cats 6 months of age or older may be tested for heartworm infections before being treated with Revolution Plus.
Revolution Plus contains an additional active ingredient in the form of sarolaner compared to Revolution (selamectin). This adds multiple tick coverage (lone star tick, Gulf Coast tick, American dog tick & black-legged tick) to Revolution Plus. In addition, the combination of sarolaner and selamectin provides a unique dual-action adulticide activity against fleas and ear mites. This formula broadens the coverage, including the most common parasites, such as fleas, flea tapeworms, ticks, ear mites, roundworms, hookworms, and heartworm disease.
According to the clinical studies, Revolution Plus is well-tolerated in cats and kittens at the recommended dose.
Rated 4.7/5 based on 1153 ratings
Revolution Plus feels more complete and gives better confidence overall.
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Revolution Plus gives better peace of mind since it covers more compared to basic versions.
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Revolution Plus feels more complete than basic options.
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Feels like more complete protection compared to basic options.
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Feels like more complete protection compared to basic options.
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