Frontline Plus for Extra Large Dogs over 89 lbs (Red)

288 customer reviews
Frontline Plus for Extra Large Dogs over 89 lbs (Red)

Price: $37.41$52.37

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Frontline Plus Flea and Tick Protection for Extra Large Dogs (Red Pack)

Frontline Plus (Red) is a monthly topical flea and tick preventive treatment for extra large dogs. One easy topical application of Frontline Plus protects your extra large dog from adult fleas, flea eggs, flea larvae, chewing lice, and ticks for 30 days.

Its fast-acting and long-lasting formula kills 100% of adult fleas within 24 hours and chewing lice within 48 hours of application. Frontline Plus works against all stages of the brown dog tick, American dog tick, lone star tick, and deer tick (the one that causes Lyme disease).

Frontline Plus topical flea and tick treatment for extra large dogs is formulated with two key ingredients- fipronil and (S)-methoprene. Fipronil works by attacking the nervous system of the parasites, while (s)-Methoprene inhibits the growth of juvenile stages of parasites and prevents further re-infestations.

Frontline Plus spot-on treatment is waterproof after 24 hours, so it remains effective even if your dog gets wet. The Red-colored pack of Frontline Plus is ideal for extra large dogs weighing over 89lbs.

Frontline Spray

Frontline Spray is an effective and unique solution designed for both cats and dogs. It efficiently treats flea and tick infestations in dogs, cats, puppies, and kittens. This treatment eliminates 100% fleas within 24 hours of administration. The frontline spray also effectively controls brown dog ticks when applied on a monthly basis and paralysis ticks in every 3 weeks of application. It is a highly recommended remedy which regulates Flea Allergy Dermatitis (FAD) as well. More Info on Frontline Spray.

  • Topical treatment for flea and tick infestations
  • Kills fleas, lone star ticks, American ticks, brown dog ticks and deer ticks
  • Suitable for all breeds of 8 weeks and older puppies and dogs
  • Waterproof treatment that remains effective even after swimming and bathing
  • Protects against flea and tick borne diseases
  • Aids in treatment of Flea Allergy Dermatitis (FAD)
  • As per the weight and size of dogs, Frontline Plus is made available in four different color-coded packs. Please refer the dosage table for details.
  • Weigh your pet and choose the appropriate pack. Part the fur behind the neck of the pet. Make sure it is between the shoulder blades so that the animal cannot lick it.
  • Place the tip of the pipette on the spot and squeeze out all the content. Allow the application site to be dry. For small dogs and medium-sized dogs, apply at just one spot while for larger dogs apply at 4-5 spots moving across the backbone to the base of the tail.
  • It is recommended for breeding, pregnant and nursing female dogs while it is advised to take veterinarian guidance before treating sick, aged and debilitated dogs with Frontline Plus.
    • Dosage:

      Color Code


      Dog Size


      0.67 ml

      0-22 lbs


      1.34 ml

      23-44 lbs


      2.68 ml

      45-88 lbs


      4.02 ml

      89-132 lbs

  • Do not treat puppies under 8 weeks of age with Frontline Plus.
  • Do not use on cats or other animals.
  • Let the application site be completely dry. Do not allow your dog to lick the application site.
  • Do not allow children and other pets to groom or play with the treated animal until the applied site is completely dry.
  • Keep away from pet’s eyes and mouth.
  • If the solution enters the pet’s eyes accidentally then flush with a lot of water.
  • It contains inflammable substance and so needs to be kept away from excessive heat or fire.
  • Keep away from children, food items and animal feeds.
  • Do not drink or smoke while applying the treatment.
  • It proves toxic for human consumption. In case of accidental ingestion contact Poison Control Center at the earliest.
  • Fipronil
  • (S)-methoprene
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MsgIcon Customer Reviews (288)
Frontline Plus for Dogs

Rated 4.9/5 based on 288 ratings

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Alvi Alford
Great service and great prices

Easy to use website. Quick shipping. Lot's of generics.

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Melissa Fischer

I had a good experience, I received both email and texts advising of delivery date and time. The package arrived in good condition. A good place to shop.

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James Skobel
heartworm medicine

good price

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Barbara Mccans
Great company

Delivers what they say!

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Philip Schneider
Great service and products

Return customer

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Have A Question?
What differences between frontline plus comb and frontline plus
Frontline Combo shows the same benefits as the Frontline Plus whereas the difference lies in their names depending on the countries where they are sold.
| May 12, 2022
(17) | (4)
Does Frontline Plus cause skin irritation?
| Mar 29, 2022
(17) | (4)
Can a very small dose be used on grown cats? I have the small mm applicator.
cat should be 8 weeks old.
| Jan 02, 2022
(17) | (2)
Can I put a second application of Frontline flea treatment on my dog if I did not apply the first dose correctly?
Please ask your Vet
| Aug 02, 2021
(17) | (3)
what is the difference between Frontline plus and spot on?
Both products kill fleas and ticks on your pet, however, FRONTLINE Plus also stops flea eggs from hatching and infesting your home.
| Jul 01, 2021
(17) | (5)
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