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Frontline Plus Purple is the leading name in flea and tick protection. This fast-acting and long-lasting topical treatment offers comprehensive protection against fleas and ticks. It effectively kills all life stages of fleas, including eggs, larvae, and pupae, as well as all stages of ticks—larvae, nymphs, and adults. This means your dog is protected not only from visible parasites but also from the hidden, immature stages of these pests that may be present in your home.
Frontline Plus for Large Dogs has been trusted by dog parents for over 20 years. It effectively protects against parasites that can transmit harmful diseases, such as Lyme disease and Rocky Mountain Spotted Fever. Frontline Plus for 45 – 88 lbs Dogs is generally considered safe for most dog breeds, including pregnant, breeding, and nursing dogs. With just one application each month, it provides year-round protection from a variety of parasites for your furry friends.
Fipronil 9.8%, S-methoprene 8.8%
| Dog Size | Dog Weight (lbs) | Pack Color | Tube Volume (ml) | Active Ingredients (g/L) | Doses Administered |
| Small Dogs | Up to 22.0 | Orange | 0.67 | 9.8% Fipronil 8.8% (S)-methoprene |
One |
| Medium Dogs | 22.1 – 44.0 | Blue | 1.34 | 9.8% Fipronil 8.8% (S)-methoprene |
One |
| Large Dogs | 44.1 – 88.0 | Purple | 2.68 | 9.8% Fipronil 8.8% (S)-methoprene |
One |
| Extra Large Dogs | Over 88 | Red | 4.02 | 9.8% Fipronil 8.8% (S)-methoprene |
One |
Frontline Plus for Dogs is for external use on puppies and dogs only. Do not administer it orally. It is not indicated for use in cats or humans. You should keep this topical product out of the reach of children, uninformed people and pets. Do not allow children or anyone to come in contact with the application site until the application is dry.
Frontline Plus can be used in pregnant, breeding and lactating dogs, when applied as indicated. Ensure to avoid the product's contact with the pet's eyes or mouth. It is not suitable for use in puppies younger than 8 weeks of age or weighing less than 5 lbs. Do not allow your dog to ingest the treatment.
Do not use or store the product near heat or open flame. Avoid contaminating water, food or feed during storage and disposal. Wash your hands thoroughly after handling the product.
Storage Guide:
Store unused Frontline Plus in the original container.
Rated 4.8/5 based on 518 ratings
I've used this several times over the years and keep coming back because I know how to apply it and my dog handles it well. Simple is sometimes better for us.
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Tried a couple of other brands out of curiosity over the years but I always come back to Frontline Plus. My three dogs all take it monthly with zero problems. It's just reliable. Consistent. Not exciting but it does exactly what I need it to do every sing
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I've gone back to Frontline Plus a few times over the years because it's familiar and has always been easy for me to use.
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Frontline Plus has stayed part of our routine for years and still works fine for regular prevention.
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Been using Frontline Plus on and off for years now and it still works fine for basic flea prevention.
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